BDBM50292173 CHEMBL4162019

SMILES: COc1ccccc1-c1cc(C)c(Nc2ccnc(Nc3ccc(cc3)C#N)n2)c(C)c1

InChI Key: InChIKey=AFUGPLVMIXYSOF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50292173 (CHEMBL4162019) Show SMILES COc1ccccc1-c1cc(C)c(Nc2ccnc(Nc3ccc(cc3)C#N)n2)c(C)c1 Show InChI InChI=1S/C26H23N5O/c1-17-14-20(22-6-4-5-7-23(22)32-3)15-18(2)25(17)30-24-12-13-28-26(31-24)29-21-10-8-19(16-27)9-11-21/h4-15H,1-3H3,(H2,28,29,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...				Eur J Med Chem 145: 726-734 (2018) Article DOI: 10.1016/j.ejmech.2018.01.016 BindingDB Entry DOI: 10.7270/Q21C20DV
					More data for this Ligand-Target Pair