BDBM50292224 1-(2-Diethylamino-ethyl)-3-hydroxy-2-oxo-3-phenyl-4-trifluoromethyl-2,3-dihydro-1H-indole-6-carboxylic acid amide::CHEMBL181312

SMILES: CCN(CC)CCN1C(=O)C(O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1

InChI Key: InChIKey=VAEJGCPNIKWEIU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50292224 (1-(2-Diethylamino-ethyl)-3-hydroxy-2-oxo-3-phenyl-...) Show SMILES CCN(CC)CCN1C(=O)C(O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1 Show InChI InChI=1S/C22H24F3N3O3/c1-3-27(4-2)10-11-28-17-13-14(19(26)29)12-16(22(23,24)25)18(17)21(31,20(28)30)15-8-6-5-7-9-15/h5-9,12-13,31H,3-4,10-11H2,1-2H3,(H2,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation				Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD
					More data for this Ligand-Target Pair