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SMILES: Cc1cccc(C)c1-c1cc(C)c(Nc2ccnc(Nc3ccc(cc3)C#N)n2)c(C)c1

InChI Key: InChIKey=FHLDQZZHWVOPOC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292234   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50292234
PNG
(CHEMBL4164636)
Show SMILES Cc1cccc(C)c1-c1cc(C)c(Nc2ccnc(Nc3ccc(cc3)C#N)n2)c(C)c1
Show InChI InChI=1S/C27H25N5/c1-17-6-5-7-18(2)25(17)22-14-19(3)26(20(4)15-22)31-24-12-13-29-27(32-24)30-23-10-8-21(16-28)9-11-23/h5-15H,1-4H3,(H2,29,30,31,32)
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Article
PubMed
n/an/a 37n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...

Eur J Med Chem 145: 726-734 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.016
BindingDB Entry DOI: 10.7270/Q21C20DV
More data for this
Ligand-Target Pair