BDBM50293717 CHEMBL572346::N-(3,4-dimethoxyphenyl)picolinamide::cid_2447227

SMILES: COc1ccc(NC(=O)c2ccccn2)cc1OC

InChI Key: InChIKey=MUFYBHIXCJGGTP-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50293717 (CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...) Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VT1QHF
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat))	BDBM50293717 (CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...) Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux				J Med Chem 52: 4115-8 (2009) Article DOI: 10.1021/jm9005065 BindingDB Entry DOI: 10.7270/Q2RJ4JHT
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50293717 (CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...) Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization				J Med Chem 52: 4115-8 (2009) Article DOI: 10.1021/jm9005065 BindingDB Entry DOI: 10.7270/Q2RJ4JHT
					More data for this Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor (Rattus norvegicus)	BDBM50293717 (CHEMBL572346 | N-(3,4-dimethoxyphenyl)picolinamide...) Show SMILES COc1ccc(NC(=O)c2ccccn2)cc1OC Show InChI InChI=1S/C14H14N2O3/c1-18-12-7-6-10(9-13(12)19-2)16-14(17)11-5-3-4-8-15-11/h3-9H,1-2H3,(H,16,17)	PDB KEGG GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DR2SWV
					More data for this Ligand-Target Pair