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BDBM50293718 CHEMBL561835::N-(3-methoxy-4-methylphenyl)picolinamide::cid_44191178

SMILES: COc1cc(NC(=O)c2ccccn2)ccc1C

InChI Key: InChIKey=MIPWAABDGPOHJQ-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293718   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293718
PNG
(CHEMBL561835 | N-(3-methoxy-4-methylphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1C
Show InChI InChI=1S/C14H14N2O2/c1-10-6-7-11(9-13(10)18-2)16-14(17)12-5-3-4-8-15-12/h3-9H,1-2H3,(H,16,17)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a 562n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2VT1QHF
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50293718
PNG
(CHEMBL561835 | N-(3-methoxy-4-methylphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1C
Show InChI InChI=1S/C14H14N2O2/c1-10-6-7-11(9-13(10)18-2)16-14(17)12-5-3-4-8-15-12/h3-9H,1-2H3,(H,16,17)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 560n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilization


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGlu4)


(Rattus norvegicus (Rat))
BDBM50293718
PNG
(CHEMBL561835 | N-(3-methoxy-4-methylphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1C
Show InChI InChI=1S/C14H14N2O2/c1-10-6-7-11(9-13(10)18-2)16-14(17)12-5-3-4-8-15-12/h3-9H,1-2H3,(H,16,17)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 210n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux


J Med Chem 52: 4115-8 (2009)


Article DOI: 10.1021/jm9005065
BindingDB Entry DOI: 10.7270/Q2RJ4JHT
More data for this
Ligand-Target Pair
glutamate receptor, metabotropic 4 precursor


(Rattus norvegicus)
BDBM50293718
PNG
(CHEMBL561835 | N-(3-methoxy-4-methylphenyl)picolin...)
Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1C
Show InChI InChI=1S/C14H14N2O2/c1-10-6-7-11(9-13(10)18-2)16-14(17)12-5-3-4-8-15-12/h3-9H,1-2H3,(H,16,17)
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/an/an/a 208n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...


PubChem Bioassay (2010)


Article DOI: 10.1111/cbdd.12243
BindingDB Entry DOI: 10.7270/Q2DR2SWV
More data for this
Ligand-Target Pair