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SMILES: Cc1csc(NC(=O)c2cc(Sc3nncn3C)ccc2Sc2ccc(F)cc2)n1

InChI Key: InChIKey=WZYQJHUWLLZEDH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294465   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hexokinase-4


(Homo sapiens (Human))		BDBM50294465
PNG
(2-(4-fluorophenylthio)-5-(4-methyl-4H-1,2,4-triazo...)
Show SMILES Cc1csc(NC(=O)c2cc(Sc3nncn3C)ccc2Sc2ccc(F)cc2)n1
Show InChI InChI=1S/C20H16FN5OS3/c1-12-10-28-19(23-12)24-18(27)16-9-15(30-20-25-22-11-26(20)2)7-8-17(16)29-14-5-3-13(21)4-6-14/h3-11H,1-2H3,(H,23,24,27)
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MMDB

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Similars
Article
PubMed
n/an/an/an/a 970n/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Activation of glucokinase

Bioorg Med Chem Lett 19: 2718-21 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.137
BindingDB Entry DOI: 10.7270/Q24M94J9
More data for this
Ligand-Target Pair