null
SMILES: OC(=O)Cc1ccccc1Nc1c(F)cccc1F
InChI Key: InChIKey=KHNKXTYWNSVJPN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50295279 (2-(2-(2,6-difluorophenylamino)phenyl)acetic acid |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Inhibition of purified mouse COX-2 assessed as inhibition of PGE2-G/PGD2-G formation preincubated for 3 mins before 2-AG substrate addition measured ... | Bioorg Med Chem Lett 23: 5860-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.097 BindingDB Entry DOI: 10.7270/Q2SB48P0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-8 (Homo sapiens (Human)) | BDBM50295279 (2-(2-(2,6-difluorophenylamino)phenyl)acetic acid |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Grupo Uriach Curated by ChEMBL | Assay Description Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assay | Bioorg Med Chem Lett 19: 4026-30 (2009) Article DOI: 10.1016/j.bmcl.2009.06.027 BindingDB Entry DOI: 10.7270/Q2V124TW | |||||||||||
More data for this Ligand-Target Pair |