BDBM50295565 3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-8-methyl-2H-pyrido[1,2-a]pyrimidine perchlorate::CHEMBL559299

SMILES: Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1

InChI Key: InChIKey=CXECSXRYGXYCAR-UHFFFAOYSA-O

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50295565 (3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-8-meth...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C22H19BrN2O/c1-15-10-11-25-14-19(13-24-21(25)12-15)22(26)18-4-2-16(3-5-18)17-6-8-20(23)9-7-17/h2-12,19H,13-14H2,1H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse iNOS expressed in insect Sf9 cells by competitive binding assay				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50295565 (3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-8-meth...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C22H19BrN2O/c1-15-10-11-25-14-19(13-24-21(25)12-15)22(26)18-4-2-16(3-5-18)17-6-8-20(23)9-7-17/h2-12,19H,13-14H2,1H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as NADPH consumption after 2 mins by spectrophotometry				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric Oxide Synthase, inducible (Mus musculus (mouse))	BDBM50295565 (3-[4'-(4''-Bromophenyl)benzoyl]-3,4-dihydro-8-meth...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(Br)cc1 Show InChI InChI=1S/C22H19BrN2O/c1-15-10-11-25-14-19(13-24-21(25)12-15)22(26)18-4-2-16(3-5-18)17-6-8-20(23)9-7-17/h2-12,19H,13-14H2,1H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair