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BDBM50295673 Benzylcarbamic acid 4-(4,5-dihydrothiazol-2-yl)phenyl ester::CHEMBL557437

SMILES: O=C(NCc1ccccc1)Oc1ccc(cc1)C1=NCCS1

InChI Key: InChIKey=LQQDVCSMYNMOTN-UHFFFAOYSA-N

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295673
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50295673 (Benzylcarbamic acid 4-(4,5-dihydrothiazol-2-yl)phe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of MGL in Wistar rat cerebral membrane by HPLC				Eur J Med Chem 44: 2994-3008 (2009) Article DOI: 10.1016/j.ejmech.2009.01.007 BindingDB Entry DOI: 10.7270/Q2VT1S5S
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50295673 (Benzylcarbamic acid 4-(4,5-dihydrothiazol-2-yl)phe...) Show SMILES Show InChI	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of FAAH in Wistar rat cerebral membrane by liquid scintillation counting				Eur J Med Chem 44: 2994-3008 (2009) Article DOI: 10.1016/j.ejmech.2009.01.007 BindingDB Entry DOI: 10.7270/Q2VT1S5S
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair