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SMILES: CC1CC(C)CN(CC(O)CO\N=C(/Cl)c2nc3ccccc3o2)C1

InChI Key: InChIKey=RAYBYLNFQKRJTQ-FXBPSFAMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat shock factor protein 1


(Homo sapiens (Human))		BDBM50295788
PNG
(CHEMBL561119 | N-(3-(3,5-dimethylpiperidin-1-yl)-2...)
Show SMILES CC1CC(C)CN(CC(O)CO\N=C(/Cl)c2nc3ccccc3o2)C1
Show InChI InChI=1S/C18H24ClN3O3/c1-12-7-13(2)9-22(8-12)10-14(23)11-24-21-17(19)18-20-15-5-3-4-6-16(15)25-18/h3-6,12-14,23H,7-11H2,1-2H3/b21-17-
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Article
PubMed
n/an/an/an/a 1.74E+4n/an/an/an/a



CytRx Corporation

Curated by ChEMBL


Assay Description
Transcriptional activation of HSF1 in heat shock stress-induced human HeLa cells assessed as granule formation treated 1 hr before heat shock challen...

Bioorg Med Chem Lett 19: 3128-35 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.011
BindingDB Entry DOI: 10.7270/Q23B605H
More data for this
Ligand-Target Pair