BDBM50295972 (3R,6S,7aS)-6-amino-6-isopropyl-5-oxohexahydropyrrolo[2,1-b]thiazole-3-carbonitrile hydrochloride::CHEMBL564854

SMILES: CC(C)[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O

InChI Key: InChIKey=PHHPHCXYJVYFHJ-WEDXCCLWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295972   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50295972 ((3R,6S,7aS)-6-amino-6-isopropyl-5-oxohexahydropyrr...) Show SMILES CC(C)[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O |r| Show InChI InChI=1S/C10H15N3OS/c1-6(2)10(12)3-8-13(9(10)14)7(4-11)5-15-8/h6-8H,3,5,12H2,1-2H3/t7-,8+,10+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Phenomix Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP4 by fluorescence assay				Bioorg Med Chem Lett 19: 4437-40 (2009) Article DOI: 10.1016/j.bmcl.2009.05.048 BindingDB Entry DOI: 10.7270/Q2571C1Z
					More data for this Ligand-Target Pair
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50295972 ((3R,6S,7aS)-6-amino-6-isopropyl-5-oxohexahydropyrr...) Show SMILES CC(C)[C@@]1(N)C[C@@H]2SC[C@@H](C#N)N2C1=O |r| Show InChI InChI=1S/C10H15N3OS/c1-6(2)10(12)3-8-13(9(10)14)7(4-11)5-15-8/h6-8H,3,5,12H2,1-2H3/t7-,8+,10+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Phenomix Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant FAP expressed in Sf9 cells by fluorescence assay				Bioorg Med Chem Lett 19: 4437-40 (2009) Article DOI: 10.1016/j.bmcl.2009.05.048 BindingDB Entry DOI: 10.7270/Q2571C1Z
					More data for this Ligand-Target Pair