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BDBM50296083 4-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)butanoic acid::CHEMBL560385

SMILES: OC(=O)CCCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1

InChI Key: InChIKey=LGRLMXKAPOROQF-GXDHUFHOSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296083   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296083
PNG
(4-(5-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-3,...)
Show SMILES OC(=O)CCCN1CCc2c(C1)c1ccccc1n2Cc1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Show InChI InChI=1S/C33H30ClN3O2/c34-26-13-11-25-12-15-27(35-30(25)20-26)14-10-23-5-3-6-24(19-23)21-37-31-8-2-1-7-28(31)29-22-36(18-16-32(29)37)17-4-9-33(38)39/h1-3,5-8,10-15,19-20H,4,9,16-18,21-22H2,(H,38,39)/b14-10+
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair