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BDBM50296099 3-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-9H-carbazol-3-yl)propanoic acid::CHEMBL562930

SMILES: OC(=O)CCc1ccc2n(Cc3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3)c3ccccc3c2c1

InChI Key: InChIKey=CWMGLOOAUHZUQW-RIYZIHGNSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296099   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50296099
PNG
(3-(9-(3-(2-(7-chloroquinolin-2-yl)vinyl)benzyl)-9H...)
Show SMILES OC(=O)CCc1ccc2n(Cc3cccc(\C=C\c4ccc5ccc(Cl)cc5n4)c3)c3ccccc3c2c1
Show InChI InChI=1S/C33H25ClN2O2/c34-26-13-11-25-12-15-27(35-30(25)20-26)14-8-22-4-3-5-24(18-22)21-36-31-7-2-1-6-28(31)29-19-23(9-16-32(29)36)10-17-33(37)38/h1-9,11-16,18-20H,10,17,21H2,(H,37,38)/b14-8+
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.80n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Displacement of [3H]LTD4 from CYSLT1 receptor in guinea pig lung membrane

Bioorg Med Chem Lett 19: 4299-302 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.094
BindingDB Entry DOI: 10.7270/Q2CN73Z1
More data for this
Ligand-Target Pair