BDBM50296297 3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiophen-2-yl)benzamide::CHEMBL563632

SMILES: COc1ccc(cc1OCCO)C(=O)Nc1ccc(Cc2cccc(c2)C(F)(F)F)s1

InChI Key: InChIKey=RWLJEWOYURWKLV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase 1 (Homo sapiens (Human))	BDBM50296297 (3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...) Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1ccc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C22H20F3NO4S/c1-29-18-7-5-15(13-19(18)30-10-9-27)21(28)26-20-8-6-17(31-20)12-14-3-2-4-16(11-14)22(23,24)25/h2-8,11,13,27H,9-10,12H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate				Bioorg Med Chem Lett 19: 4159-66 (2009) Article DOI: 10.1016/j.bmcl.2009.05.123 BindingDB Entry DOI: 10.7270/Q2PZ58VW
					More data for this Ligand-Target Pair
Acyl-CoA desaturase 1 (Mus musculus)	BDBM50296297 (3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...) Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1ccc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C22H20F3NO4S/c1-29-18-7-5-15(13-19(18)30-10-9-27)21(28)26-20-8-6-17(31-20)12-14-3-2-4-16(11-14)22(23,24)25/h2-8,11,13,27H,9-10,12H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate				Bioorg Med Chem Lett 19: 4159-66 (2009) Article DOI: 10.1016/j.bmcl.2009.05.123 BindingDB Entry DOI: 10.7270/Q2PZ58VW
					More data for this Ligand-Target Pair