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BDBM50296312 3-(2-hydroxyethoxy)-4-(methylsulfonamido)-N-(5-(3-(trifluoromethyl)benzyl)thiazol-2-yl)benzamide::CHEMBL563099

SMILES: CS(=O)(=O)Nc1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1

InChI Key: InChIKey=ZQZJCYDPADMMDT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296312   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Mus musculus)		BDBM50296312
PNG
(3-(2-hydroxyethoxy)-4-(methylsulfonamido)-N-(5-(3-...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1
Show InChI InChI=1S/C21H20F3N3O5S2/c1-34(30,31)27-17-6-5-14(11-18(17)32-8-7-28)19(29)26-20-25-12-16(33-20)10-13-3-2-4-15(9-13)21(22,23)24/h2-6,9,11-12,27-28H,7-8,10H2,1H3,(H,25,26,29)
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate

Bioorg Med Chem Lett 19: 4159-66 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW
More data for this
Ligand-Target Pair