BDBM50297346 CHEMBL4167741

SMILES: COc1cc2c(Oc3ccc(NC(=O)NN4C(SCC4=O)c4c(F)cccc4F)cc3)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=OHEKPYDPMXZOGA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50297346 (CHEMBL4167741) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NN4C(SCC4=O)c4c(F)cccc4F)cc3)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C33H33F2N5O5S/c1-43-28-18-23-26(19-29(28)44-17-5-16-39-14-2-3-15-39)36-13-12-27(23)45-22-10-8-21(9-11-22)37-33(42)38-40-30(41)20-46-32(40)31-24(34)6-4-7-25(31)35/h4,6-13,18-19,32H,2-3,5,14-17,20H2,1H3,(H2,37,38,42)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0370	n/a	n/a	n/a	n/a	n/a	n/a
Zhuhai Campus of Zunyi Medical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA				Eur J Med Chem 146: 368-380 (2018) Article DOI: 10.1016/j.ejmech.2018.01.061 BindingDB Entry DOI: 10.7270/Q2BP059Q
					More data for this Ligand-Target Pair