BDBM50297489 3-(hydroxyimino)-1-(3-methylbenzyl)indolin-2-one::CHEMBL557971

SMILES: Cc1cccc(CN2C(=O)C(N=O)c3ccccc23)c1

InChI Key: InChIKey=UNKPTFFOMJTTFC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50297489 (3-(hydroxyimino)-1-(3-methylbenzyl)indolin-2-one |...) Show SMILES Cc1cccc(CN2C(=O)C(N=O)c3ccccc23)c1 Show InChI InChI=1S/C16H14N2O2/c1-11-5-4-6-12(9-11)10-18-14-8-3-2-7-13(14)15(17-20)16(18)19/h2-9,15H,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of JNK3 by spectrophotometric coupled enzyme assay				Bioorg Med Chem Lett 19: 2891-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.043 BindingDB Entry DOI: 10.7270/Q2F76CMZ
					More data for this Ligand-Target Pair