BDBM50297901 4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamido)propyl)piperazine-1-carboximidamide::CHEMBL550881

SMILES: COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=HBMLSWFKFNOFCI-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50297901 (4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12 |w:16.18| Show InChI InChI=1S/C25H31N5O3S/c1-33-23-12-5-4-11-22(23)29-16-18-30(19-17-29)25(26)27-14-7-15-28-34(31,32)24-13-6-9-20-8-2-3-10-21(20)24/h2-6,8-13,28H,7,14-19H2,1H3,(H2,26,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50297901 (4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12 |w:16.18| Show InChI InChI=1S/C25H31N5O3S/c1-33-23-12-5-4-11-22(23)29-16-18-30(19-17-29)25(26)27-14-7-15-28-34(31,32)24-13-6-9-20-8-2-3-10-21(20)24/h2-6,8-13,28H,7,14-19H2,1H3,(H2,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT2A receptor in rat cortex				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50297901 (4-(2-methoxyphenyl)-N-(3-(naphthalene-1-sulfonamid...) Show SMILES COc1ccccc1N1CCN(CC1)C(N)=NCCCNS(=O)(=O)c1cccc2ccccc12 |w:16.18| Show InChI InChI=1S/C25H31N5O3S/c1-33-23-12-5-4-11-22(23)29-16-18-30(19-17-29)25(26)27-14-7-15-28-34(31,32)24-13-6-9-20-8-2-3-10-21(20)24/h2-6,8-13,28H,7,14-19H2,1H3,(H2,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor in rat hippocampus				Bioorg Med Chem Lett 19: 4827-31 (2009) Article DOI: 10.1016/j.bmcl.2009.06.038 BindingDB Entry DOI: 10.7270/Q20G3M3C
					More data for this Ligand-Target Pair