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SMILES: COc1ccc(cc1F)C1=NOC(C1)c1noc(n1)-c1cccc(OC)c1OC

InChI Key: InChIKey=JIMSLYLACPDQDA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298013 (5-(2,3-dimethoxyphenyl)-3-(3-(3-fluoro-4-methoxyph...) Show SMILES COc1ccc(cc1F)C1=NOC(C1)c1noc(n1)-c1cccc(OC)c1OC |t:10| Show InChI InChI=1S/C20H18FN3O5/c1-25-15-8-7-11(9-13(15)21)14-10-17(28-23-14)19-22-20(29-24-19)12-5-4-6-16(26-2)18(12)27-3/h4-9,17H,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298013 (5-(2,3-dimethoxyphenyl)-3-(3-(3-fluoro-4-methoxyph...) Show SMILES COc1ccc(cc1F)C1=NOC(C1)c1noc(n1)-c1cccc(OC)c1OC |t:10| Show InChI InChI=1S/C20H18FN3O5/c1-25-15-8-7-11(9-13(15)21)14-10-17(28-23-14)19-22-20(29-24-19)12-5-4-6-16(26-2)18(12)27-3/h4-9,17H,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair