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SMILES: Oc1ccc(cc1F)C1=NOC(Cc2noc(n2)C(F)(F)F)C1

InChI Key: InChIKey=PGMMADDADWXKEP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298027 (2-fluoro-4-(5((5-(trifluoromethyl)-1,2,4-oxadiazol...) Show SMILES Oc1ccc(cc1F)C1=NOC(Cc2noc(n2)C(F)(F)F)C1 |t:9| Show InChI InChI=1S/C13H9F4N3O3/c14-8-3-6(1-2-10(8)21)9-4-7(22-19-9)5-11-18-12(23-20-11)13(15,16)17/h1-3,7,21H,4-5H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of human recombinant MIF				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298027 (2-fluoro-4-(5((5-(trifluoromethyl)-1,2,4-oxadiazol...) Show SMILES Oc1ccc(cc1F)C1=NOC(Cc2noc(n2)C(F)(F)F)C1 |t:9| Show InChI InChI=1S/C13H9F4N3O3/c14-8-3-6(1-2-10(8)21)9-4-7(22-19-9)5-11-18-12(23-20-11)13(15,16)17/h1-3,7,21H,4-5H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of dopachrome tautomerase activity of MIF in human THP1 cells				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50298027 (2-fluoro-4-(5((5-(trifluoromethyl)-1,2,4-oxadiazol...) Show SMILES Oc1ccc(cc1F)C1=NOC(Cc2noc(n2)C(F)(F)F)C1 |t:9| Show InChI InChI=1S/C13H9F4N3O3/c14-8-3-6(1-2-10(8)21)9-4-7(22-19-9)5-11-18-12(23-20-11)13(15,16)17/h1-3,7,21H,4-5H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Piramal Life Sciences Curated by ChEMBL					Assay Description Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISA				Bioorg Med Chem Lett 19: 4773-6 (2009) Article DOI: 10.1016/j.bmcl.2009.06.052 BindingDB Entry DOI: 10.7270/Q2Z0387W
					More data for this Ligand-Target Pair