BDBM50298373 4,5-Bis[2-(N,N-dimethylamino)ethylaminomethyl]acridine::CHEMBL574042

SMILES: CN(C)CCNCc1cccc2cc3cccc(CNCCN(C)C)c3nc12

InChI Key: InChIKey=BJIRXSJANCOMSK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50298373 (4,5-Bis[2-(N,N-dimethylamino)ethylaminomethyl]acri...) Show SMILES CN(C)CCNCc1cccc2cc3cccc(CNCCN(C)C)c3nc12 Show InChI InChI=1S/C23H33N5/c1-27(2)13-11-24-16-20-9-5-7-18-15-19-8-6-10-21(23(19)26-22(18)20)17-25-12-14-28(3)4/h5-10,15,24-25H,11-14,16-17H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Reims-Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of human telomerase in A549 cells by TRAP assay				Eur J Med Chem 44: 3880-8 (2009) Article DOI: 10.1016/j.ejmech.2009.04.021 BindingDB Entry DOI: 10.7270/Q2W37WDH
					More data for this Ligand-Target Pair