null

SMILES: COC(=O)c1ccc(cc1)\N=C\c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=SONMMTHLONHMSH-DEDYPNTBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50299297 (CHEMBL572526 | methyl 4-(4-tert-butylbenzylideneam...) Show SMILES COC(=O)c1ccc(cc1)\N=C\c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H21NO2/c1-19(2,3)16-9-5-14(6-10-16)13-20-17-11-7-15(8-12-17)18(21)22-4/h5-13H,1-4H3/b20-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCM-UMII-CNRS 5635 Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration by stopped flow technique				Bioorg Med Chem Lett 19: 6014-7 (2009) Article DOI: 10.1016/j.bmcl.2009.09.047 BindingDB Entry DOI: 10.7270/Q2FQ9WP1
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50299297 (CHEMBL572526 | methyl 4-(4-tert-butylbenzylideneam...) Show SMILES COC(=O)c1ccc(cc1)\N=C\c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H21NO2/c1-19(2,3)16-9-5-14(6-10-16)13-20-17-11-7-15(8-12-17)18(21)22-4/h5-13H,1-4H3/b20-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCM/UMII/UMR-CNRS 5635 Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay				Bioorg Med Chem 22: 2867-74 (2014) Article DOI: 10.1016/j.bmc.2014.03.041 BindingDB Entry DOI: 10.7270/Q27D2WPD
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50299297 (CHEMBL572526 | methyl 4-(4-tert-butylbenzylideneam...) Show SMILES COC(=O)c1ccc(cc1)\N=C\c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C19H21NO2/c1-19(2,3)16-9-5-14(6-10-16)13-20-17-11-7-15(8-12-17)18(21)22-4/h5-13H,1-4H3/b20-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ENSCM/UMII/UMR-CNRS 5635 Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assay				Bioorg Med Chem 22: 2867-74 (2014) Article DOI: 10.1016/j.bmc.2014.03.041 BindingDB Entry DOI: 10.7270/Q27D2WPD
					More data for this Ligand-Target Pair