null

SMILES: COc1cc2ncnc(Nc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC

InChI Key: InChIKey=BEYUGPLUWSNIHT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50299779 (CHEMBL573765 | N-(4-(6,7-dimethoxyquinazolin-4-yla...) Show SMILES COc1cc2ncnc(Nc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC Show InChI InChI=1S/C26H23FN6O4/c1-36-22-13-18-21(14-23(22)37-2)28-15-29-24(18)31-20-9-8-16(12-19(20)27)30-25(34)33-11-10-32(26(33)35)17-6-4-3-5-7-17/h3-9,12-15H,10-11H2,1-2H3,(H,30,34)(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of TPR-Met assessed as autophosphorylation				Bioorg Med Chem Lett 19: 6552-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.040 BindingDB Entry DOI: 10.7270/Q2VM4D6R
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50299779 (CHEMBL573765 | N-(4-(6,7-dimethoxyquinazolin-4-yla...) Show SMILES COc1cc2ncnc(Nc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC Show InChI InChI=1S/C26H23FN6O4/c1-36-22-13-18-21(14-23(22)37-2)28-15-29-24(18)31-20-9-8-16(12-19(20)27)30-25(34)33-11-10-32(26(33)35)17-6-4-3-5-7-17/h3-9,12-15H,10-11H2,1-2H3,(H,30,34)(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc Curated by ChEMBL					Assay Description Inhibition of GST-tagged c-Met expressed in Sf9 cells				Bioorg Med Chem Lett 19: 6552-6 (2009) Article DOI: 10.1016/j.bmcl.2009.10.040 BindingDB Entry DOI: 10.7270/Q2VM4D6R
					More data for this Ligand-Target Pair