BDBM50299941 (6-chloro-4-methyl-2-oxo-1,4-dihydro-2H-3,1-benzoxazin-4-yl)methyl(4-fluorophenyl)carbamate::CHEMBL570350

SMILES: CC1(COC(=O)Nc2ccc(F)cc2)OC(=O)Nc2ccc(Cl)cc12

InChI Key: InChIKey=ARQXNSIYPYSEPY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Elongation of very long chain fatty acids protein 6 (Homo sapiens (Human))	BDBM50299941 ((6-chloro-4-methyl-2-oxo-1,4-dihydro-2H-3,1-benzox...) Show SMILES CC1(COC(=O)Nc2ccc(F)cc2)OC(=O)Nc2ccc(Cl)cc12 Show InChI InChI=1S/C17H14ClFN2O4/c1-17(9-24-15(22)20-12-5-3-11(19)4-6-12)13-8-10(18)2-7-14(13)21-16(23)25-17/h2-8H,9H2,1H3,(H,20,22)(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assay				J Med Chem 52: 7289-300 (2009) Article DOI: 10.1021/jm900915x BindingDB Entry DOI: 10.7270/Q2XK8FMB
					More data for this Ligand-Target Pair