Found 12 hits for monomerid = 50301098 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melanin-concentrating hormone receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of delta-type opioid receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Melanin-concentrating hormone receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPR |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human ERG potassium channel 1 |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of mu-type opioid receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of muscarinic M1 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H1 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H2 Receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H2 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H3 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of histamine H4 receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Adenosine receptor A2a
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of adenosine receptor A2A |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50301098
(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)Show InChI InChI=1S/C23H26FN3O2/c1-2-11-25-15-19-5-8-21(26-16-19)9-12-27-13-10-22(14-23(27)28)29-17-18-3-6-20(24)7-4-18/h3-8,10,13-14,16,25H,2,9,11-12,15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tsukuba Research Institute
Curated by ChEMBL
| Assay Description Inhibition of kappa-type opioid receptor |
Bioorg Med Chem Lett 19: 5186-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.023 BindingDB Entry DOI: 10.7270/Q2G44QCG |
More data for this Ligand-Target Pair | |