BDBM50301694 5-(5-((4-isopropylpiperazin-1-yl)methyl)furan-3-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL568371

SMILES: CC(C)N1CCN(Cc2cc(co2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key: InChIKey=YTAXZQBKZAMFER-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50301694 (5-(5-((4-isopropylpiperazin-1-yl)methyl)furan-3-yl...) Show SMILES CC(C)N1CCN(Cc2cc(co2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C27H30N6O/c1-18(2)33-10-8-32(9-11-33)16-22-12-20(17-34-22)24-15-29-14-21(13-28)27(24)31-25-4-5-26-23(19(25)3)6-7-30-26/h4-7,12,14-15,17-18,30H,8-11,16H2,1-3H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50301694 (5-(5-((4-isopropylpiperazin-1-yl)methyl)furan-3-yl...) Show SMILES CC(C)N1CCN(Cc2cc(co2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C27H30N6O/c1-18(2)33-10-8-32(9-11-33)16-22-12-20(17-34-22)24-15-29-14-21(13-28)27(24)31-25-4-5-26-23(19(25)3)6-7-30-26/h4-7,12,14-15,17-18,30H,8-11,16H2,1-3H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP kinase assay				Bioorg Med Chem Lett 19: 5423-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.109 BindingDB Entry DOI: 10.7270/Q2V69JPF
					More data for this Ligand-Target Pair