BDBM50302036 5-(5-((4-ethylpiperazin-1-yl)methyl)benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL570713

SMILES: CCN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key: InChIKey=GXRHJQDLOAPBIK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50302036 (5-(5-((4-ethylpiperazin-1-yl)methyl)benzofuran-2-y...) Show SMILES CCN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C30H30N6O/c1-3-35-10-12-36(13-11-35)19-21-4-7-28-22(14-21)15-29(37-28)25-18-32-17-23(16-31)30(25)34-26-5-6-27-24(20(26)2)8-9-33-27/h4-9,14-15,17-18,33H,3,10-13,19H2,1-2H3,(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta by IMAP fluorescence polarization technology				Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50302036 (5-(5-((4-ethylpiperazin-1-yl)methyl)benzofuran-2-y...) Show SMILES CCN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C30H30N6O/c1-3-35-10-12-36(13-11-35)19-21-4-7-28-22(14-21)15-29(37-28)25-18-32-17-23(16-31)30(25)34-26-5-6-27-24(20(26)2)8-9-33-27/h4-9,14-15,17-18,33H,3,10-13,19H2,1-2H3,(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP fluorescence polarization technology				Bioorg Med Chem Lett 19: 5799-802 (2009) Article DOI: 10.1016/j.bmcl.2009.07.113 BindingDB Entry DOI: 10.7270/Q2QR4Z2Q
					More data for this Ligand-Target Pair