BDBM50302358 CHEMBL568145::N-(1-(4'-(3-propoxyphenoxy)biphenyl-4-yl)ethyl)-1H-pyrazole-4-carboxamide

SMILES: CCCOc1cccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(=O)c2cn[nH]c2)c1

InChI Key: InChIKey=INITZJYAMOMMSL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM50302358 (CHEMBL568145 | N-(1-(4'-(3-propoxyphenoxy)biphenyl...) Show SMILES CCCOc1cccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(=O)c2cn[nH]c2)c1 Show InChI InChI=1S/C27H27N3O3/c1-3-15-32-25-5-4-6-26(16-25)33-24-13-11-22(12-14-24)21-9-7-20(8-10-21)19(2)30-27(31)23-17-28-29-18-23/h4-14,16-19H,3,15H2,1-2H3,(H,28,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	609	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 2 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human))	BDBM50302358 (CHEMBL568145 | N-(1-(4'-(3-propoxyphenoxy)biphenyl...) Show SMILES CCCOc1cccc(Oc2ccc(cc2)-c2ccc(cc2)C(C)NC(=O)c2cn[nH]c2)c1 Show InChI InChI=1S/C27H27N3O3/c1-3-15-32-25-5-4-6-26(16-25)33-24-13-11-22(12-14-24)21-9-7-20(8-10-21)19(2)30-27(31)23-17-28-29-18-23/h4-14,16-19H,3,15H2,1-2H3,(H,28,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC 1 expressed in baculovirus expression system by FAS-coupled assay				Bioorg Med Chem Lett 19: 5872-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.077 BindingDB Entry DOI: 10.7270/Q24J0F6F
					More data for this Ligand-Target Pair