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SMILES: CCCCS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1

InChI Key: InChIKey=HIVMNLBUPXZGPA-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304990   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))		BDBM50304990
PNG
((S)-4-((1-(butylsulfonyl)pyrrolidin-3-yl)(2-(trifl...)
Show SMILES CCCCS(=O)(=O)N1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r|
Show InChI InChI=1S/C23H25ClF3N3O2S/c1-2-3-12-33(31,32)29-11-10-20(16-29)30(19-9-8-17(14-28)22(24)13-19)15-18-6-4-5-7-21(18)23(25,26)27/h4-9,13,20H,2-3,10-12,15-16H2,1H3/t20-/m0/s1
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KEGG

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PC cid
PC sid
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Patents

Similars
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of PR

Bioorg Med Chem Lett 20: 371-4 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.092
BindingDB Entry DOI: 10.7270/Q2057G17
More data for this
Ligand-Target Pair