BDBM50306191 2-(4-((N,1-dimethylpiperidine-3-carboxamido)methyl)phenyl)-2H-indazole-7-carboxamide::CHEMBL605725

SMILES: CN(Cc1ccc(cc1)-n1cc2cccc(C(N)=O)c2n1)C(=O)C1CCCN(C)C1

InChI Key: InChIKey=MYEWDYUTQCYOKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50306191 (2-(4-((N,1-dimethylpiperidine-3-carboxamido)methyl...) Show SMILES CN(Cc1ccc(cc1)-n1cc2cccc(C(N)=O)c2n1)C(=O)C1CCCN(C)C1 Show InChI InChI=1S/C23H27N5O2/c1-26-12-4-6-18(14-26)23(30)27(2)13-16-8-10-19(11-9-16)28-15-17-5-3-7-20(22(24)29)21(17)25-28/h3,5,7-11,15,18H,4,6,12-14H2,1-2H3,(H2,24,29)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assay				Bioorg Med Chem Lett 20: 488-92 (2010) Article DOI: 10.1016/j.bmcl.2009.11.127 BindingDB Entry DOI: 10.7270/Q2W37WFZ
					More data for this Ligand-Target Pair