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SMILES: C[C@H](O)CN1[C@H](COc2c1cccc2-c1cccc(OC(F)(F)F)c1)c1cccc(OC(F)(F)C(F)F)c1

InChI Key: InChIKey=KRNJEUKTVDSZSR-OYHNWAKOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306619   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50306619
PNG
((S)-1-((S)-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)...)
Show SMILES C[C@H](O)CN1[C@H](COc2c1cccc2-c1cccc(OC(F)(F)F)c1)c1cccc(OC(F)(F)C(F)F)c1 |r|
Show InChI InChI=1S/C26H22F7NO4/c1-15(35)13-34-21-10-4-9-20(16-5-2-8-19(11-16)38-26(31,32)33)23(21)36-14-22(34)17-6-3-7-18(12-17)37-25(29,30)24(27)28/h2-12,15,22,24,35H,13-14H2,1H3/t15-,22+/m0/s1
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n/an/a 88n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human cholesteryl ester transfer protein by scintillation proximity assay

Bioorg Med Chem Lett 20: 1432-5 (2010)


Article DOI: 10.1016/j.bmcl.2009.12.096
BindingDB Entry DOI: 10.7270/Q2WW7HRC
More data for this
Ligand-Target Pair