BDBM50307331 (2-Carbamimidoylbenzo[b]thiophen-6-yloxy)thiophen-2-ylacetic Acid Ethyl Ester::CHEMBL596950

SMILES: COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1cccs1

InChI Key: InChIKey=SLKMBSWRTAUUSA-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307331 ((2-Carbamimidoylbenzo[b]thiophen-6-yloxy)thiophen-...) Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1cccs1 Show InChI InChI=1S/C22H18N2O3S2/c1-26-22(25)20(18-6-3-9-28-18)27-16-5-2-4-13(11-16)14-7-8-17-15(10-14)12-19(29-17)21(23)24/h2-12,20H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1465-72 (2010) Article DOI: 10.1021/jm901475e BindingDB Entry DOI: 10.7270/Q22N5372
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307331 ((2-Carbamimidoylbenzo[b]thiophen-6-yloxy)thiophen-...) Show SMILES COC(=O)C(Oc1cccc(c1)-c1ccc2sc(cc2c1)C(N)=N)c1cccs1 Show InChI InChI=1S/C22H18N2O3S2/c1-26-22(25)20(18-6-3-9-28-18)27-16-5-2-4-13(11-16)14-7-8-17-15(10-14)12-19(29-17)21(23)24/h2-12,20H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10 by amidolytic assay				J Med Chem 53: 1465-72 (2010) Article DOI: 10.1021/jm901475e BindingDB Entry DOI: 10.7270/Q22N5372
					More data for this Ligand-Target Pair