BDBM50307334 5-(3,4-Dimethoxyphenyl)benzo[b]thiophene-2-carboxamidine::CHEMBL598384
SMILES: COc1ccc(cc1OC)-c1ccc2sc(cc2c1)C(N)=N
InChI Key: InChIKey=FHFYJPXHDJXVJS-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor IX (Homo sapiens (Human)) | BDBM50307334 (5-(3,4-Dimethoxyphenyl)benzo[b]thiophene-2-carboxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | MMDB Article PubMed | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant factor 9a by amidolytic assay | J Med Chem 53: 1465-72 (2010) Article DOI: 10.1021/jm901475e BindingDB Entry DOI: 10.7270/Q22N5372 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50307334 (5-(3,4-Dimethoxyphenyl)benzo[b]thiophene-2-carboxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd. Curated by ChEMBL | Assay Description Inhibition of factor 10 by amidolytic assay | J Med Chem 53: 1465-72 (2010) Article DOI: 10.1021/jm901475e BindingDB Entry DOI: 10.7270/Q22N5372 | |||||||||||
More data for this Ligand-Target Pair |