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BDBM50311318 6-bromo-N-(2-chlorophenyl)-2-methylimidazo[1,2-a]pyridine-3-carboxamide::CHEMBL1077741

SMILES: Cc1nc2ccc(Br)cn2c1C(=O)Nc1ccccc1Cl

InChI Key: InChIKey=ZUSNVDFABMKMFR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311318   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311318
PNG
(6-bromo-N-(2-chlorophenyl)-2-methylimidazo[1,2-a]p...)
Show SMILES Cc1nc2ccc(Br)cn2c1C(=O)Nc1ccccc1Cl
Show InChI InChI=1S/C15H11BrClN3O/c1-9-14(20-8-10(16)6-7-13(20)18-9)15(21)19-12-5-3-2-4-11(12)17/h2-8H,1H3,(H,19,21)
PDB
MMDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 173n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair