BDBM50311429 9-Hydroxymethyl-4-methyl-9-morpholin-4-ylmethyl-8, 9-dihydro-pyrano[2,3-f]chromene-2,10-dione::CHEMBL1077922

SMILES: Cc1cc(=O)oc2c3C(=O)C(CO)(CN4CCOCC4)COc3ccc12

InChI Key: InChIKey=AWWKJLYPHDHQCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50311429 (9-Hydroxymethyl-4-methyl-9-morpholin-4-ylmethyl-8,...) Show SMILES Cc1cc(=O)oc2c3C(=O)C(CO)(CN4CCOCC4)COc3ccc12 Show InChI InChI=1S/C19H21NO6/c1-12-8-15(22)26-17-13(12)2-3-14-16(17)18(23)19(10-21,11-25-14)9-20-4-6-24-7-5-20/h2-3,8,21H,4-7,9-11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem Lett 19: 6447-51 (2009) Article DOI: 10.1016/j.bmcl.2009.09.031 BindingDB Entry DOI: 10.7270/Q2930T8Z
					More data for this Ligand-Target Pair