null

SMILES: N[C@H](CNc1nnc(s1)-c1ccc2[nH]ncc2c1)Cc1ccc(Cl)cc1

InChI Key: InChIKey=NHCKWRFRGQYSQI-HNNXBMFYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50312749 ((S)-N1-(5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)...) Show SMILES N[C@H](CNc1nnc(s1)-c1ccc2[nH]ncc2c1)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H17ClN6S/c19-14-4-1-11(2-5-14)7-15(20)10-21-18-25-24-17(26-18)12-3-6-16-13(8-12)9-22-23-16/h1-6,8-9,15H,7,10,20H2,(H,21,25)(H,22,23)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 1652-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.046 BindingDB Entry DOI: 10.7270/Q21836MC
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50312749 ((S)-N1-(5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl)...) Show SMILES N[C@H](CNc1nnc(s1)-c1ccc2[nH]ncc2c1)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C18H17ClN6S/c19-14-4-1-11(2-5-14)7-15(20)10-21-18-25-24-17(26-18)12-3-6-16-13(8-12)9-22-23-16/h1-6,8-9,15H,7,10,20H2,(H,21,25)(H,22,23)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of AKT1 after 10 mins by [gamma33]ATP assay				Bioorg Med Chem Lett 20: 1652-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.046 BindingDB Entry DOI: 10.7270/Q21836MC
					More data for this Ligand-Target Pair