BDBM50313373 (5R,7S,8R,9R,10S)-7-(3-(4-ethylbenzyl)-4-methylphenyl)-1,6-dioxaspiro[4.5]decane-8,9,10-triol::CHEMBL1094714

SMILES: CCc1ccc(Cc2cc(ccc2C)[C@@H]2O[C@]3(CCCO3)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=DDOXILQISMHBNE-URYYLNOGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313373   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50313373 ((5R,7S,8R,9R,10S)-7-(3-(4-ethylbenzyl)-4-methylphe...) Show SMILES CCc1ccc(Cc2cc(ccc2C)[C@@H]2O[C@]3(CCCO3)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C24H30O5/c1-3-16-6-8-17(9-7-16)13-19-14-18(10-5-15(19)2)22-20(25)21(26)23(27)24(29-22)11-4-12-28-24/h5-10,14,20-23,25-27H,3-4,11-13H2,1-2H3/t20-,21-,22+,23+,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs				Bioorg Med Chem Lett 20: 1569-72 (2010) Article DOI: 10.1016/j.bmcl.2010.01.075 BindingDB Entry DOI: 10.7270/Q2DF6RBP
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50313373 ((5R,7S,8R,9R,10S)-7-(3-(4-ethylbenzyl)-4-methylphe...) Show SMILES CCc1ccc(Cc2cc(ccc2C)[C@@H]2O[C@]3(CCCO3)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C24H30O5/c1-3-16-6-8-17(9-7-16)13-19-14-18(10-5-15(19)2)22-20(25)21(26)23(27)24(29-22)11-4-12-28-24/h5-10,14,20-23,25-27H,3-4,11-13H2,1-2H3/t20-,21-,22+,23+,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs				Bioorg Med Chem Lett 20: 1569-72 (2010) Article DOI: 10.1016/j.bmcl.2010.01.075 BindingDB Entry DOI: 10.7270/Q2DF6RBP
					More data for this Ligand-Target Pair