null

SMILES: OC(C(N1CCCC1)c1ccccc1)(c1cccnc1)c1cccnc1

InChI Key: InChIKey=KVQINTYARDHBBP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50315583 (2-phenyl-1,1-di(pyridin-3-yl)-2-(pyrrolidin-1-yl)e...) Show SMILES OC(C(N1CCCC1)c1ccccc1)(c1cccnc1)c1cccnc1 Show InChI InChI=1S/C22H23N3O/c26-22(19-10-6-12-23-16-19,20-11-7-13-24-17-20)21(25-14-4-5-15-25)18-8-2-1-3-9-18/h1-3,6-13,16-17,21,26H,4-5,14-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 20: 2493-6 (2010) Article DOI: 10.1016/j.bmcl.2010.03.005 BindingDB Entry DOI: 10.7270/Q2T153SV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 5 (Homo sapiens (Human))	BDBM50315583 (2-phenyl-1,1-di(pyridin-3-yl)-2-(pyrrolidin-1-yl)e...) Show SMILES OC(C(N1CCCC1)c1ccccc1)(c1cccnc1)c1cccnc1 Show InChI InChI=1S/C22H23N3O/c26-22(19-10-6-12-23-16-19,20-11-7-13-24-17-20)21(25-14-4-5-15-25)18-8-2-1-3-9-18/h1-3,6-13,16-17,21,26H,4-5,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	284	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in CHO cells by whole cell patch clamp assay				Bioorg Med Chem Lett 20: 2493-6 (2010) Article DOI: 10.1016/j.bmcl.2010.03.005 BindingDB Entry DOI: 10.7270/Q2T153SV
					More data for this Ligand-Target Pair