BDBM50315937 (S)-N-ethyl-4-fluoro-3-methyl-N-(2-(1-phenylethylamino)pyrimidin-4-yl)benzamide::CHEMBL1090891

SMILES: CCN(C(=O)c1ccc(F)c(C)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1

InChI Key: InChIKey=YSZQYJIYTFITQG-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315937 ((S)-N-ethyl-4-fluoro-3-methyl-N-(2-(1-phenylethyla...) Show SMILES CCN(C(=O)c1ccc(F)c(C)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C22H23FN4O/c1-4-27(21(28)18-10-11-19(23)15(2)14-18)20-12-13-24-22(26-20)25-16(3)17-8-6-5-7-9-17/h5-14,16H,4H2,1-3H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair