BDBM50316030 1-aminopentylphosphonic acid::CHEMBL1089899::Nle-P (3)

SMILES: CCCCC(N)P(O)(O)=O

InChI Key: InChIKey=NXTPDFMZKSLVRK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine aminopeptidase (LAP) (Sus scrofa (Pig))	BDBM50316030 (1-aminopentylphosphonic acid | CHEMBL1089899 | Nle...) Show SMILES CCCCC(N)P(O)(O)=O Show InChI InChI=1S/C5H14NO3P/c1-2-3-4-5(6)10(7,8)9/h5H,2-4,6H2,1H3,(H2,7,8,9)	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+4	-5.78	n/a	n/a	n/a	n/a	n/a	8.4	25
Academy of Sciences of the Czech Republic					Assay Description LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...				J Enzyme Inhib Med Chem 26: 155-61 (2011) Article DOI: 10.3109/14756366.2010.482047 BindingDB Entry DOI: 10.7270/Q22N515B
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50316030 (1-aminopentylphosphonic acid | CHEMBL1089899 | Nle...) Show SMILES CCCCC(N)P(O)(O)=O Show InChI InChI=1S/C5H14NO3P/c1-2-3-4-5(6)10(7,8)9/h5H,2-4,6H2,1H3,(H2,7,8,9)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate				Bioorg Med Chem 18: 2930-6 (2010) Article DOI: 10.1016/j.bmc.2010.02.056 BindingDB Entry DOI: 10.7270/Q2FN16C0
					More data for this Ligand-Target Pair