BDBM50316177 2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-pyrimidin-2-ylpiperidin-4-yl]carbonyl}methylsulfamate::CHEMBL1092612

SMILES: COc1cccc(c1)C1(CCN(CC1)c1ncccn1)C(=O)N(C)S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C

InChI Key: InChIKey=SZWOPUDSMVTWCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50316177 (2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-pyrim...) Show SMILES COc1cccc(c1)C1(CCN(CC1)c1ncccn1)C(=O)N(C)S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C30H38N4O5S/c1-21(2)25-12-8-13-26(22(3)4)27(25)39-40(36,37)33(5)28(35)30(23-10-7-11-24(20-23)38-6)14-18-34(19-15-30)29-31-16-9-17-32-29/h7-13,16-17,20-22H,14-15,18-19H2,1-6H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat macrophages ACAT				J Med Chem 53: 3284-95 (2010) Article DOI: 10.1021/jm901909p BindingDB Entry DOI: 10.7270/Q2639PWV
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