Found 16 hits for monomerid = 50316788 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 250 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 250 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 250 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of EGFR after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISA |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Inhibition of EGFR after 30 mins by chemiluminescence ELISA |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Inhibition of IGF1R after 30 mins by chemiluminescence ELISA |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50316788
(4-(2-(3-amino-9-(5-phenylpentyl)-2,3,4,4a,9,9a-hex...)Show SMILES NC1CCc2c(C1)c1cc(OCCc3ccc(O)cc3)ccc1n2CCCCCc1ccccc1 Show InChI InChI=1S/C31H36N2O2/c32-25-12-16-30-28(21-25)29-22-27(35-20-18-24-10-13-26(34)14-11-24)15-17-31(29)33(30)19-6-2-5-9-23-7-3-1-4-8-23/h1,3-4,7-8,10-11,13-15,17,22,25,34H,2,5-6,9,12,16,18-21,32H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t Leipzig
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATP |
Bioorg Med Chem 18: 3387-402 (2010)
Article DOI: 10.1016/j.bmc.2010.04.001 BindingDB Entry DOI: 10.7270/Q21836NT |
More data for this Ligand-Target Pair | |