BDBM50316856 4'-(4-Aminobenzensulfonamide)-4-hydroxychalcone::CHEMBL1087578
SMILES: Nc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)cc1
InChI Key: InChIKey=HMCALLLWIUWUTM-LZWSPWQCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50316856 (4'-(4-Aminobenzensulfonamide)-4-hydroxychalcone | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Functional Crop Curated by ChEMBL | Assay Description Competitive inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50316856 (4'-(4-Aminobenzensulfonamide)-4-hydroxychalcone | ...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Functional Crop Curated by ChEMBL | Assay Description Inhibition of monophenolase activity of mushroom tyrosinase using as L-tyrosine substrate by spectrophotometric analysis | Eur J Med Chem 45: 2010-7 (2010) Article DOI: 10.1016/j.ejmech.2010.01.049 BindingDB Entry DOI: 10.7270/Q2H70FZM | |||||||||||
More data for this Ligand-Target Pair |