BDBM50317108 2-(1-{(2S)-3-[(6-Chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl}piperidin-4-yl)-1,2-dihydro-3H-pyrrolo[1,2-c]imidazol-3-one::CHEMBL1087230

SMILES: O[C@H](CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C(=O)N1CCC(CC1)N1Cc2cccn2C1=O

InChI Key: InChIKey=CQWUDWSWXJFXHG-JOCHJYFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50317108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50317108 (2-(1-{(2S)-3-[(6-Chloronaphthalen-2-yl)sulfonyl]-2...) Show SMILES O[C@H](CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C(=O)N1CCC(CC1)N1Cc2cccn2C1=O |r| Show InChI InChI=1S/C24H24ClN3O5S/c25-18-5-3-17-13-21(6-4-16(17)12-18)34(32,33)15-22(29)23(30)26-10-7-19(8-11-26)28-14-20-2-1-9-27(20)24(28)31/h1-6,9,12-13,19,22,29H,7-8,10-11,14-15H2/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Inhibition of human factor 10a assessed as p-nitroanilide release using S2765 as substrate by chromogenic assay				J Med Chem 53: 3517-31 (2010) Article DOI: 10.1021/jm901699j BindingDB Entry DOI: 10.7270/Q2PR7W52
					More data for this Ligand-Target Pair