BDBM50317480 (S)-2-(2-((4-(4-chlorophenoxy)phenoxy)methyl)piperidin-1-yl)acetic acid::CHEMBL1098170
SMILES: OC(=O)CN1CCCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1
InChI Key: InChIKey=UONPGQMBZPLCLV-INIZCTEOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50317480 ((S)-2-(2-((4-(4-chlorophenoxy)phenoxy)methyl)piper...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MS | Bioorg Med Chem Lett 20: 2851-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.047 BindingDB Entry DOI: 10.7270/Q2CC10VD | |||||||||||
More data for this Ligand-Target Pair |