BDBM50317490 (R/S)-2-((4-benzylphenoxy)methyl)piperazine::CHEMBL1098820
SMILES: C(Oc1ccc(Cc2ccccc2)cc1)C1CNCCN1
InChI Key: InChIKey=NQEDMJQVVYPBBZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A4 hydrolase (Homo sapiens (Human)) | BDBM50317490 ((R/S)-2-((4-benzylphenoxy)methyl)piperazine | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 342 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry, Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MS | Bioorg Med Chem Lett 20: 2851-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.047 BindingDB Entry DOI: 10.7270/Q2CC10VD | |||||||||||
More data for this Ligand-Target Pair |