BDBM50317590 (-)-R-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpiperazin-1-yl)ethyl)cyclohexanol::CHEMBL1099178

SMILES: CN1CCN(C[C@@H](c2csc(Cl)c2)C2(O)CCCCC2)CC1

InChI Key: InChIKey=KHYNNQYNYMSTIB-HNNXBMFYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50317590 ((-)-R-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpipe...) Show SMILES CN1CCN(C[C@@H](c2csc(Cl)c2)C2(O)CCCCC2)CC1 |r| Show InChI InChI=1S/C17H27ClN2OS/c1-19-7-9-20(10-8-19)12-15(14-11-16(18)22-13-14)17(21)5-3-2-4-6-17/h11,13,15,21H,2-10,12H2,1H3/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human NET transfected in MDCK-Net6 cells				Bioorg Med Chem Lett 20: 2809-12 (2010) Article DOI: 10.1016/j.bmcl.2010.03.059 BindingDB Entry DOI: 10.7270/Q2028RQV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50317590 ((-)-R-1-(1-(5-chlorothiophen-3-yl)-2-(4-methylpipe...) Show SMILES CN1CCN(C[C@@H](c2csc(Cl)c2)C2(O)CCCCC2)CC1 |r| Show InChI InChI=1S/C17H27ClN2OS/c1-19-7-9-20(10-8-19)12-15(14-11-16(18)22-13-14)17(21)5-3-2-4-6-17/h11,13,15,21H,2-10,12H2,1H3/t15-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 form human DAT expressed in CHO cell membranes				Bioorg Med Chem Lett 20: 2809-12 (2010) Article DOI: 10.1016/j.bmcl.2010.03.059 BindingDB Entry DOI: 10.7270/Q2028RQV
					More data for this Ligand-Target Pair