null
SMILES: O[C@@]1(C[C@@H](CSC#N)O[C@H]([C@@H]1c1ccccc1)c1ccccc1)c1ccccc1
InChI Key: InChIKey=ASFZJMRECGOZIJ-QORCZRPOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50317928 ((2R*,3S*,4R*,6S*)-Tetrahydro-2,3,4-triphenyl-6-(th...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Guru Nanak Dev University Curated by ChEMBL | Assay Description Inhibition of ovine COX1 assessed as inhibition of PGF2a formation after 20 mins by Ellman's method | J Med Chem 53: 3707-17 (2010) Article DOI: 10.1021/jm1001327 BindingDB Entry DOI: 10.7270/Q2NP24KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM50317928 ((2R*,3S*,4R*,6S*)-Tetrahydro-2,3,4-triphenyl-6-(th...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55 | n/a | n/a | n/a | n/a | n/a | n/a |
Guru Nanak Dev University Curated by ChEMBL | Assay Description Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's method | J Med Chem 53: 3707-17 (2010) Article DOI: 10.1021/jm1001327 BindingDB Entry DOI: 10.7270/Q2NP24KF | |||||||||||
More data for this Ligand-Target Pair |