BDBM50318364 3-phenyl-5-((2-(trifluoromethyl)phenoxy)methyl)oxazolidin-2-one::CHEMBL1098725

SMILES: FC(F)(F)c1ccccc1OCC1CN(C(=O)O1)c1ccccc1

InChI Key: InChIKey=SAASZOVUMKTLAZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50318364 (3-phenyl-5-((2-(trifluoromethyl)phenoxy)methyl)oxa...) Show SMILES FC(F)(F)c1ccccc1OCC1CN(C(=O)O1)c1ccccc1 Show InChI InChI=1S/C17H14F3NO3/c18-17(19,20)14-8-4-5-9-15(14)23-11-13-10-21(16(22)24-13)12-6-2-1-3-7-12/h1-9,13H,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...				Bioorg Med Chem Lett 20: 3129-33 (2010) Article DOI: 10.1016/j.bmcl.2010.03.089 BindingDB Entry DOI: 10.7270/Q2Z038B7
					More data for this Ligand-Target Pair