BDBM50318557 (1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol-4-yl)propylamino)cyclohexane-1,2,3,4,5-pentaol::CHEMBL1083794

SMILES: CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1

InChI Key: InChIKey=WESSLVVPBLSCJX-XLGNRPJKSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318557 ((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318557 ((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.4	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318557 ((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetry				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50318557 ((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...) Show SMILES CCCCCCCCCCn1cc(CCCN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1 |r| Show InChI InChI=1S/C21H40N4O5/c1-2-3-4-5-6-7-8-9-13-25-14-15(23-24-25)11-10-12-22-16-17(26)19(28)21(30)20(29)18(16)27/h14,16-22,26-30H,2-13H2,1H3/t16-,17-,18+,19+,20-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	5.2	n/a
Universitat de Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry				J Med Chem 53: 5248-55 (2010) Article DOI: 10.1021/jm100198t BindingDB Entry DOI: 10.7270/Q2VH5PS1
					More data for this Ligand-Target Pair